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The CREID
Network
Vol. 2, Issue 2 | April 2024

Dedicated to addressing critical research areas in emerging infectious diseases and development of regional scientific expertise and research capacity.
Image caption: 2023 CREID Pilot Program Awardee Miguel Garcia Knight, PhD (EpiCenter) of National Autonomous University in Mexico, is conducting research in Mexico and Uganda studying mosquito vectors.

CREID Network Updates


The Centers for Research in Emerging Infectious Diseases (CREID) Network is funded by the National Institute of Allergy and Infectious Diseases of the U.S. National Institutes of Health and is comprised of 10 Research Centers and 1 Coordinating Center.
 

Network by the Numbers


Click on the image to learn more about where the CREID Network works.

CREID Network Impact


Since the start of the CREID Network in 2020, Research Center researchers have published more than 550 publications as reflected in the Publication Dashboard on the CREID Network website.

Additionally, members of Research Centers have collaborated on research and training efforts across Centers, with results leading to collaborative publications as seen in the table below on topics such as the SARS-CoV-2 pandemic, Dengue outbreaks, prototype pathogens, and arbovirus surveillance efforts.

CREID Network Collaborative Publications

2020-2024

Research Centers Title Journal Title Journal Volume Publication Date Authors
A2CARES, CREATE-NEO Real-time RT-PCR for Venezuelan equine encephalitis complex, Madariaga, and Eastern equine encephalitis viruses: Application in human and mosquito public health surveillance in Panama Journal of Clinical Microbiology 61 19-Dec-23 Carrera, J-P; et. al.
CREATE-NEO, UWARN Dynamic clade transitions and the influence of vaccine rollout on the spatiotemporal circulation of SARS-CoV-2 variants in São Paulo, Brazil Research Square   22-Jan-24 Banho, CA; et. al.
CREATE-NEO, UWARN SARS-CoV-2 Spillback to Wild Coatis in Sylvatic-Urban Hotspot, Brazil Emerging Infectious Diseases 29 Mar-23 Stoffella-Dutra, AG; et. al.
CREATE-NEO, UWARN Genomic epidemiology of the SARS-CoV-2 epidemic in Brazil Nature Mircrobiology 7 Sep-22 Giovanetti, M; et. al. 
CREATE-NEO, UWARN Genomic epidemiology reveals the impact of national and international restrictions measures on the SARS-CoV-2 epidemic in Brazil medRxiv : the preprint server for Health Sciences   28-Mar-22 Giovanetti, M; et. al. 
CREID-ESP, WAC-EID Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies Nature Medicine 27 Apr-21 Chen RE; et. al. 
PICREID, WAC-EID Reemergence of Sylvatic Dengue Virus Serotype 2 in Kedougou, Senegal, 2020 Emerging Infectious Diseases 30 Apr-24 Dieng, I; et. al.
PICREID, WAC-EID Analysis of a Dengue Virus Outbreak in Rosso, Senegal 2021 Tropical Medicine and Infectious Disease 7 7-Dec-22 Dieng, I; et. al.
UWARN, WARN-ID Detection of SARS-CoV-2 in Terrestrial Animals in Southern Nigeria: Potential Cases of Reverse Zoonosis Viruses 15 17-May-23 Happi, AN; et. al.
UWARN, WARN-ID The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance Science (New York, N.Y.) 378 7-Oct-23 Tegall, H; et. al. 
WAC-EID, WARN-ID The Arenaviridae Family: Knowledge Gaps, Animal Models, Countermeasures, and Prototype Pathogens The Journal of Infectious Diseases 228 18-Oct-23 Hastie, KM; et. al.
For the full list and details of CREID publications, visit the CREID website at
https://creid-network.org/publications

Stakeholder News


The CREID Network collaborates with a wide variety of external stakeholders including from the US Government, foreign governments, multilateral institutions such as the World Health Organization, foundations and nonprofits, such as CEPI, Wellcome Foundation, and the private sector. If you are interested in exploring a collaboration with the CREID Network, please contact info@creid-network.org
 



WHO's Science in 5 - Disease X

WHO is a CREID Network stakeholder and a WHO representative sits on the CREID Network External Advisory Committee. 

How are scientists working to prevent the next pandemic? What do countries need to do to prepare? Ana Maria Henao-Restrepo outlines the R&D needs that the world needs to invest in to prevent and prepare for the next pandemic.

Research Center Updates


The April 2024 quarterly newsletter features 2 of the CREID Research Centers: CREATE-NEO and UWARN. In addition to working in the US, these 2 Research Centers work in Brazil and Panama (CREATE-NEO); and Brazil, Pakistan, Senegal, South Africa, Switzerland, and Taiwan.

Please see more information about each of the 10 Research Centers at the CREID Network website.

 

CREATE-NEO/FAMERP Postdoctoral Fellow Dr. Lívia Sacchetto trains colleagues from Paraguay’s Universidad Nacional de Asunción on next-generation sequencing (NGS) for real-time genomic surveillance and outbreak research.

CREATE-NEO


CREATE-NEO investigators at the Faculdade de Medicina de São José do Rio Preto (FAMERP) alerted Brazilian health authorities to impending explosive twin outbreaks, after identifying cryptic chikungunya virus circulation in humans and vectors and the emergence of Dengue virus serotype-3 to naïve populations. Concurrently, the program expanded regional capacity for real-time genomic surveillance and outbreak research through South-to-South training and support.

Award Number U01AI151807

UWARN


UWARN partners, Dr. Abdou Padane and colleagues at the Institute for Health Research, Epidemiological Surveillance and Training (IRESSEF), Senegal, discovered, in real-time, an emerging clade of the Chikungunya West African genotype, phylogenetically distinct from previous outbreaks, during the 2023 CHIKV outbreak in Senegal. The Abbott Pandemic Defense Coalition (APDC) and the Center for Epidemic Response and Innovation (CERI) in South Africa, supported Dr. Padane with a fellowship to establish West African Dengue surveillance, offering protocols, reagents, consumables, ongoing data analysis assistance, and enriching his skills, which included gaining expertise in whole genome sequencing (WGS) and epidemic response. Dr. Padane utilized these skills to detect, sequence, and identify this novel CHIKV strain.

Award Number U01AI151698 



IRESSEF Implementing Whole Genome Sequencing (WGS) for genomic surveillance.
Legend, from lower left, moving counter-clockwise: Dr. Abdou Padane, who trained at CERI/APDC/UWARN, South Africa, is seen inputting parameters into an IRESSEF TapStation machine to quantify DNA fragment size before sequencing; Dr. Padane is shown training an IRESSEF team (Dr. Cyrille Diedhiou, Dr. Marièma Sarr, Mrs. Ndèye Astou Dabo, Mrs. Ndèye Dieynaba Diouf) in WGS wet-lab, the IRESSEF team (Dr. Abdou Padane, Dr. Cyrille Diedhiou, Dr. Marièma Sarr, Mrs. Ndèye Astou Dabo, Mrs. Ndèye Dieynaba Diouf) executes wet-lab WGS.

 
A2CARES
CREATE-NEO
CREID-ECA
CREID-ESP
EpiCenter
EID-SEARCH
PICREID
UWARN
WAC-EID
WARN-ID
CREID Coordinating Center * info@creid-network.org * creid-network.org

Copyright © 2024, CREID Coordinating Center, all rights reserved.


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